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Product introduction

PI3K/mTOR Inhibitor-2 is a potent dual pan- PI3K / mTOR inhibitor with IC 50 s of 3.4/34/16/1 nM for PI3Kα / PI3Kβ / PI3Kδ / PI3Kγ and 4.7 nM for mTOR Antitumor activity In Vitro PI3K/mTOR Inhibitor-2 (Compound 31) inhibits p-AKT and p-p70s6k in MCF-7 cells with IC 50 s of 11.6 and 89.2 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PI3Kα 3.4 nM (IC 50 ) PI3Kβ 34 nM (IC 50 ) PI3Kδ 16 nM (IC 50 ) PI3Kγ 1 nM (IC 50 ) mTOR 4.7 nM (IC 50 )

Specs ⸢ View details ⸥

Chinese name

PI3K/mTOR Inhibitor-2

English name

PI3K/mTOR Inhibitor-2

Chinese alias

PI3K/mTOR 抑制剂-2

English alias

CAS number

1848242-58-9

molecular formula

C20H13ClF2N4O4S

molecular weight

478.86 g/mol

Exact mass

≥98%

PSA

109.000 Å²

Logp

2.100

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