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名称

(S)-PI3Kα-IN-4

英文名称

(S)-PI3Kα-IN-4

货号

P650804-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

(S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα , with an IC 50 of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ , PI3Kδ , and PI3Kγ , respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer In Vitro (S)-PI3Kα-IN-4 (compound 11) is a quinazolin-4(3H)-one derivative with 2-substituted-N-methylpropanamide substitution. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PI3Kα 2.3 nM (IC 50 )

生化机理

(S)-PI3Kα-IN-4是一种强效的 PI3Kα 抑制剂，其 IC 50 为 2.3 nM。与 PI3Kβ、PI3Kδ 和 PI3Kγ 相比，(S)-PI3Kα-IN-4 对 PI3Kα 的选择性分别为 38.3 倍、4.25 倍和 4.93 倍。(S)-PI3Kα-IN-4可用于癌症研究。

CAS号

2322293-84-3

分子式

C25H23ClFN5O5S

分子量

560.00 g/mol

Smiles

O=C(NC)[C@@H](C)CN1C=NC2=C(C=C(C3=CC(NS(=O)(C4=CC=C(F)C=C4Cl)=O)=C(OC)N=C3)C=C2)C1=O

溶解性

DMSO : 100 mg/mL (178.57 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

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「No technical documents」

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