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Product introduction

PTC299 是 VEGFA mRNA 翻译的抑制剂，在转录后水平选择性地抑制 VEGF 蛋白的合成。PTC299 也是二氢乳酸盐脱氢酶 (DHODH) 的有效抑制剂。PTC299 良好的口服生物利用度，缺乏脱靶激酶抑制和骨髓抑制。PTC299 可用于血液系统恶性肿瘤的研究。 PTC299 is active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies.

Specs ⸢ View details ⸥

Chinese name

PTC299, 二氢烟酸脱氢酶抑制剂

English name

PTC299

Chinese alias

埃姆沃多司他

English alias

Emvododstat | (4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate | PTC299

CAS number

1256565-36-2

molecular formula

C25H20Cl2N2O3

molecular weight

467.34 g/mol

Exact mass

PSA

54.600 Å²

Logp

6.300

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PTC299 10mM in DMSO 1ml

Name: PTC299 10mM in DMSO 1ml
Brand: 麦克林
SKU: P688090-1ml

Macklin PTC299 10mM in DMSO 1ml, CAS 1256565-36-2, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：P688090-1ml

Product model：1ml

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Lead Time：30days

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PTC299 10mM in DMSO 1ml

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