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Product introduction
PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC 50 s of 97 and 23 nM, respectively. PF-4840154 elicits TrpA1-mediated nocifensive behaviour in mouse In Vivo PF-4840154 (30 nmol; intraplantar) elicits TrpA1-mediated nocifensive behaviour in mouse . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female CD1 mice (25-30g) (In TrpA1+/+ mice) Dosage: 30 nmol Administration: Intraplantar (i.pl) injection Result: Elicited robust licking behavior. Form:Solid IC50& Target:IC50: 97 nM (rTrpA1), 23 nM (hTrpA1)
Chinese name
PF-4840154
English name
PF-4840154
Chinese alias
-
English alias
N-Benzyl-4-(isobutylamino)-2-[4-(tetrahydropyran-3-ylmethyl)piperazin-1-yl]pyrimidine-5-carboxamide | PF 4840154 | SCHEMBL17185544 | F18483 | 1332708-14-1 | N-benzyl-4-(2-methylpropylamino)-2-[4-(oxan-3-ylmethyl)piperazin-1-yl]pyrimidine-5-carboxamide | E
CAS number
1332708-14-1
molecular formula
C26H38N6O2
molecular weight
466.62 g/mol
Exact mass
≥99%
PSA
82.600 Ų
Logp
4.000
Technical Documents
「No technical documents」
Related
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Articles
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PF-4840154 ≥99% 5mg

PF-4840154 ≥99% 5mg CAS 1332708-14-1, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:P883195-5mg
Product model:5mg
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Lead Time:30days
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