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Product introduction

1(R)-(Trifluoromethyl)oleyl alcohol (compound (R)-24) is a trifluoromethyl alcohol derivative of Oleic acid with activity in multiple models of Friedreich ataxia (FRDA). 1(R)-(Trifluoromethyl)oleyl alcohol inhibits ferroptosis induced by Erastin and decreases lipid peroxidation in NBT human myoblasts with frataxin (FXN) siRNA knockdown. 1(R)-(Trifluoromethyl)oleyl alcohol at 40 μM increases survival to 95% in a model of FRDA where a significant percentage of cell death is caused by FAC and BSO.

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Chinese name

1(R)-(Trifluoromethyl)oleyl alcohol

English name

1(R)-(Trifluoromethyl)oleyl alcohol

Chinese alias

English alias

CAS number

2644636-20-2

molecular formula

C19H35F3O

molecular weight

336.48 g/mol

Exact mass

PSA

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