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Product introduction

(R)-Nepicastat HCl (RS-25560-198)是Nepicastat HCl的R-对映体，是一种有效的，选择性的抑制剂，作用于牛和人类dopamine-β-hydroxylase（多巴胺-β-羟化酶），IC50分别为25.1 nM和18.3 nM，对12种其他酶和13种神经递质受体具有极其微弱的亲和力。 (R)-Nepicastat HCl (RS-25560-198), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.

Specs ⸢ View details ⸥

Chinese name

(R) -盐酸奈哌卡因

English name

(R)-Nepicastat HCl

Chinese alias

English alias

4-(aminomethyl)-3-[(2R)-5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-1H-imidazole-2-thione | hydrochloride | RS-25560-198 HCl

CAS number

195881-94-8

molecular formula

C14H15F2N3S·HCl

molecular weight

331.81 g/mol

Exact mass

≥99%

PSA

73.400 Å²

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