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Product introduction

Revexepride is a highly selective 5-HT4 receptor agonist, and a potential inducer of CYP3A4 enzyme , used for the treatment of gastroesophageal reflux disease. In Vitro The human CYP isoenzymes are involved in the metabolism of revexepride, which is mainly metabolized in vitro in humans by CYP3A4 (99.9%) with a minor contribution of CYP2D6 (0.1%). Revexepride exhibits direct inhibition of human CYP3A4 in vitro with IC 50 values of 16-49 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:5-HT 4 Receptor CYP3A4

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Chinese name

Revexepride, 羟色胺 4 (5-HT4) 受体激动剂

English name

Revexepride

Chinese alias

瑞维普利

English alias

HY-U00373 | SPD557 | SPD-557 | Revexepride | SCHEMBL505587 | 4-amino-5-chloro-N-[[(3S,4S)-3-hydroxy-1-(3-methoxypropyl)piperidin-4-yl]methyl]-2,2-dimethyl-3H-1-benzofuran-7-carboxamide | (-)-revexepride | SSP-002358 | Q27270174 | 7-BENZOFURANCARBOXAMIDE,

CAS number

219984-49-3

molecular formula

C21H32ClN3O4

molecular weight

425.95 g/mol

Exact mass

≥99%

PSA

97.100 Å²

Logp

2.3

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