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Product details

名称

Ridogrel

分子类型

小分子

别名

利多格雷

英文名称

Ridogrel

货号

R655122-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities . In Vitro In rats, R 68 070 (1.25 mg/kg orally, -2 h) singly prolongs tail bleeding times as much as a combination of TXA2 synthetase inhibition (dazoxiben 10 mg/kg) and TXA2/prostaglandin endoperoxide receptor blockade (BM 13177 40 mg/kg). In dogs, the compound reduces coronary thrombosis induced by electrical damage (1.25 mg/kg i.v.) and prevents the evolution of occlusion/reperfusion-induced arrhythmias into ventricular fibrillation (2.5 mg/kg i.v.) [2 . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

生化机理

利多格瑞（R 68070）是一种口服活性血栓素 A2 合成酶抑制剂和血栓素 A2/前列腺素内过氧化物受体阻断剂的复方制剂。利多格列是一种强效抗血小板药。抗炎活性。

CAS号

110140-89-1(DMSO)

分子式

C18H17F3N2O3

分子量

366.33 g/mol

Smiles

C1=CC(=CC(=C1)C(F)(F)F)C(=NOCCCCC(=O)O)C2=CN=CC=C2

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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