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Product details

名称

RIPK1-IN-4

分子类型

小分子

英文名称

RIPK1-IN-4

货号

R655286-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase IC50& Target:IC50: 16 nM (RIP1) and 10 nM (ADP-Glo)

生化机理

RIPK1-IN-4 （化合物 8）是受体互作蛋白 1（RIP1）激酶的一种强效、选择性 II 型激酶抑制剂，能与 DLG-out 非活性形式的 RIP1 结合，对 RIP1 和 ADP-Glo 激酶的 IC 50 s 分别为 16 nM 和 10 nM。

CAS号

1481641-08-0(DMSO)

分子式

C23H23N5O2

分子量

401.46 g/mol

Smiles

CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CC=CC4=C3C=CN=C4N

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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