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Product details

名称

RP101988

英文名称

RP101988

货号

R658962-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC 50 s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5 , respectivlely. Appearance:Solid IC50& Target:S1PR1 0.19 nM (EC 50 ) S1PR5 32.8 nM (EC 50 ) In Vitro:RP101988 is a substrate of P-gp and breast cancer resistance protein (BCRP) drug transporters. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC 50 s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5 , respectivlely.

分子式

C23H22N4O4

分子量

418.45 g/mol

Smiles

O=C(O)CN[C@H]1CCC2=C1C=CC=C2C3=NOC(C4=CC=C(OC(C)C)C(C#N)=C4)=N3

溶解性

DMSO : 125 mg/mL (298.72 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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