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名称

RI(dl)-2 TFA

别名

RI(dl)-2三氟乙酸

英文名称

RI(dl)-2 TFA

货号

R659481-5mg

包装规格

5mg

浓度

≥98%

储存温度

2-8°C储存,干燥

运输条件

冰袋运输

产品介绍

RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM. RI(dl)-2 TFA does not influence RAD51 binding to ssDNA and inhibits homologous recombination (HR) activity in human cells ( IC 50 of 3.0 μM). Appearance:Solid IC50& Target:IC50: 11.1 μM (RAD51-mediated D-loop formation) In Vitro:RI(dl)-2 stabilizes nucleoprotein filaments in a nonfunctional state, which are incapable of D-loop activity and simultaneously shielded from related (e.g., RAD52-mediated) pathways that promote single-strand annealing (SSA). RI(dl)-2 does not modula Biological Activity:RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM. RI(dl)-2 TFA does not influence RAD51 binding to ssDNA and inhibits homologous recombination (HR) activity in human cells ( IC 50 of 3.0 μM).

分子式

C19H17N3.(1.3)C2HF3O2

分子量

435.59 g/mol

Smiles

CCNC1=CC=C(C2=NC3=C(N4C2=CC=C4)C=CC=C3)C=C1.OC(C(F)(F)F)=O.[1.3]

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

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