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Product introduction
Romidepsin (FK 228) 是具有抗肿瘤活性的组蛋白去乙酰化酶 (HDAC) 抑制剂,抑制 HDAC1,HDAC2,HDAC4 和 HDAC6,IC50 值分别为 36 nM,47 nM,510 nM 和 1.4 μM。Romidepsin (FK 228) 由紫色杆菌产生,诱导 G2/M 细胞周期阻滞和凋亡 (apoptosis)。 Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis.
Chinese name
Romidepsin,HDAC1和HDAC2抑制剂, 组蛋白去乙酰化酶抑制剂
English name
Romidepsin (FK228, Depsipeptide)
Chinese alias
罗咪酯肽 | 罗米地辛
English alias
Methoxiphenadrinum | Depsipeptide | DEPSIPEPTIDE [WHO-DD] | Romidepsin (FK228) | Chromadax | L-Valine,3-didehydro-2- aminobutanoyl-,.xi.-lactone, cyclic (1.fwdarw.2)-disulfide | Piperazine, 1-(10,11-dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methy
CAS number
128517-07-7
molecular formula
C24H36N4O6S2
molecular weight
540.7 g/mol
Exact mass
-
PSA
193.000 Ų
Logp
2.2
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Luo Mi Di Xin 10mM in DMSO 1ml

Luo Mi Di Xin 10mM in DMSO 1ml Macklin 128517-07-7, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:R793819-1ml
Product model:1ml
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