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Product introduction
R406是一种有效的Syk抑制剂,IC50为41 nM,对Syk抑制作用强,但是不抑制Lyn,作用于Flt3效果弱5倍。Phase 1。 R406 is a potent Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 1. An IgE and IgG- mediated Fc signaling activation inhibitor.
Chinese name
R406
English name
R406
Chinese alias
R406苯磺酸盐 | 6-[[5-氟-2-[(3,4,5-三甲氧基苯基)氨基]-4-嘧啶基]氨基]-2,2-二甲基-2H-吡啶并[3,2-B]-1,4-恶嗪-3(4H)-酮苯磺酸盐
English alias
N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine | EX-A103-1 | N4-(2,2-dimethyl-3-oxo-4H-pyrid[1,4]oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine | R406 Benzenesulfonate |
CAS number
841290-81-1
molecular formula
C28H29FN6O8S
molecular weight
628.63 g/mol
Exact mass
≥98%
PSA
192.000 Ų
Logp
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R406 10mM in DMSO 1ml

R406 10mM in DMSO 1ml Macklin 841290-81-1, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:R797350-1ml
Product model:1ml
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Lead Time:30days
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