硅烷-PEG-丙烯酸酯

Silane-PEG-Acrylate

S164284-100mg

100mg

MW 5000 Da

-20°C储存

超低温冰袋运输

Ethoxy or methoxyl silane functionalized polyethylene glycol, silane PEG (PEG-Si) is a surface reactive PEG derivative that can be used to modify glass, silica and other surfaces via the reaction between hydroxyl group and ethoxyl/methoxyl silane. Pegylation can greatly suppress the non-specific binding of charged molecules to the modified surfaces. And they have wide applications for medica device, biomems or biocompatible material development. Ethoxy or methoxyl silane functionalized polyethylene glycol, silane PEG (PEG-Si) is a surface reactive PEG derivative that can be used to modify glass, silica and other surfaces via the reaction between hydroxyl group and ethoxyl/methoxyl silane. Pegylation can greatly suppress the non-specific binding of charged molecules to the modified surfaces. And they have wide applications for medica device, biomems or biocompatible material development.

一般来说，先将硅烷 PEG 溶解在乙醇/水的混合溶液中，然后让溶液与氧化玻璃或二氧化硅表面接触 30 分钟至 2 小时。在此条件下，硅烷 PEG 应与材料共价结合。 所需材料 聚乙二醇化溶液：乙醇/水（重量比，95%/5%）； 硅烷 PEG 储备液，10~50 mg/mL 气化溶液，新鲜配制。 洗涤液：蒸馏水。 反应步骤： 1： 1.将目标材料溶解于聚乙二醇化缓冲液中 。 2. 向目标共轭材料中加入硅烷 PEG 原液，最终浓度至少为 10 mg/mL。硅烷 PEG 的摩尔过量为 10~50，才能达到最佳共轭效果； 3. 让混合物在室温下搅拌 30 分钟，或在 4 -20 0C 下搅拌 2 小时。 4.用蒸馏水洗去未反应的物质。

Off-white/white solid or viscous liquid depends on molecule weight;Soluble in regular aqeous solution as well as most organic solvents;