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Product introduction

Lapaquistat acetate (TAK-475) 是一种角鲨烯合酶 (squalene synthase) 抑制剂，阻断胆固醇生物合成途径中法呢基二磷酸酯 (FPP) 转化为角鲨烯。Lapaquistat acetate 可有效降低低密度脂蛋白胆固醇，但可能引起肝脏损害。Lapaquistat acetate 可用于高胆固醇血症和甲羟戊酸激酶缺乏症 (MKD) 的研究。 Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway. Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research.

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Chinese name

Lapaquistat acetate (TAK-475), 角鲨烯合成酶抑制剂

English name

Lapaquistat acetate (TAK-475)

Chinese alias

拉帕司他醋酸盐 | 2-(1-(2-((3R,5S)-1-(3-乙酰氧基-2,2-二甲基丙基)-7-氯-5-(2,3-二甲氧基苯基)-2-氧代-1,2,3,5-四氢苯并[e][1,4]氧氮杂卓-3-基)乙酰基)哌啶-4-基)乙酸

English alias

2-(1-(2-((3R,5S)-1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid | Q27280898 | 2-(5,6-dimethyl-9-oxoxanthen-4-yl)acetic acid | SCHEMBL288494 | IUH3AY74O

CAS number

189060-13-7

molecular formula

C33H41ClN2O9

molecular weight

645.14 g/mol

Exact mass

PSA

132.000 Å²

Logp

3.8

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Research chemical 98% 5mg

Name: Research chemical 98% 5mg
Brand: MedMol
SKU: S20638-5mg

Research chemical 98% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：S20638-5mg

Product model：5mg

level： 98% 5mg

Lead Time：30days

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Research chemical 98% 5mg

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