Ramoplanin是一种有效的环状脂糖肽肽抗生素，据报道对需氧和厌氧革兰氏阳性细菌具有活性。机理研究表明，拉莫普林可通过与关键的中间部分脂质II结合来阻止细胞壁肽聚糖聚糖的形成和进一步的酶促加工。拉莫普林还显示出对脂质I的低亲和力，脂质I是细胞壁形成MurG步骤的底物。 Ramoplanin, a potent cyclic lipoglycodepsipeptide antibiotic, has been reported to be active against aerobic and anaerobic gram-positive bacteria. Mechanistic studies show that Ramoplanin prevents cell wall peptidoglygan formation and further enzymatic processing via binding to lipid II, a key intermediate moeity. Ramoplanin has also displayed a low affinity for Lipid I, a substrate for the MurG step of cell wall formation.