- Harmful effect： 当患者同时接受水杨酸盐、磺胺类药物、含纤维酸的药物和华法林治疗时，监测潜在的药物-药物相互作用至关重要。可能抑制或诱导CYP2C9的其他药物包括唑类抗真菌药、卡马西平、苯巴比妥、利福平、圣约翰草和地塞米松。缓解磺酰脲类和格列本脲毒性的最有益方法是将患者的血糖水平恢复到正常范围，具体取决于环境。
- Toxicity summary： 格列本脲的毒性主要与因过量服用而导致的严重低血糖风险有关，无论是意外还是故意。由于涉及CYP2C9酶的代谢重复，格列本脲与其他磺酰脲类药物之间的药物相互作用也可能增强低血糖。
- Regulatory information： 新西兰EPA化学品清单状态：格列本脲：没有单独批准，但可在适当的团体标准下使用
- Other safety information： 化学品评估：IMAP评估 - 苯甲酰胺，5-氯-N-[2-[4-[[[(环己基氨基)羰基]氨基]磺酰基]苯基]乙基]-2-甲氧基-：人类健康一级评估
- Hazard categories and classifications： 水生慢性4（93.7%）
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： 截至修订日期，未找到相关已发表信息。
- USGS Health-Based Screening Levels for Evaluating Water-Quality： 参考文献: Smith, C.D. and Nowell, L.H., 2024. 用于评估水质数据的基于健康的标准水平 (第 3 版)。DOI:10.5066/F71C1TWP
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Research chemical CAS 10238-21-8 98% 100g
Research chemical CAS 10238-21-8 98% 100g, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
