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Product introduction
L-(+)-麦角硫因适用于研究它与2,2′- 和4,4′-联吡啶二硫化物(2-Py-S-S-2-Py和4-Py-S-S-4-Py)的反应性。 它也可用于实验细胞的孵育,同时进行ATM(Ataxia毛细血管扩张症突变)或ATR (ATM-和RAD3-相关)的体外激酶活性测定。 L-(+)-麦角硫因已被用于: 1、作为卵丘-卵母细胞复合物(COC)成熟培养基的组成部分,检测其对脂质过氧化形成的保护作用; 2、作为一种抗氧化化合物用于检测2型糖尿病患者; 3、作为可溶性载体蛋白22A4 (SLC22A4)转运检测的阳性对照。 Ergothioneine is a stable antioxidant that can be found under conditions of excessive oxidative stress in plant and animal tissue. Ergothioneine can scavenge free radicals and protect cells from UV-induced ROS with higher efficiency than antioxidants coenzyme Q(10) or idebenone. The compound could be a non-toxic thiol buffering antioxidant, enhance cell viability induced by hydrogen peroxide (H2O2), and inhibit DNA oxidation by peroxynitrite (ONOO-) in the human neuronal hybridoma cell line (N-18-RE-105). An antioxidant and free radical scavenger Application: L - (+) - ergot sulfur is suitable for studying its reactivity with 2,2 '- and 4,4' - bipyridine disulfides (2-Py-S-S-2-Py and 4-Py-S-S-4-Py). It can also be used for the incubation of experimental cells and for in vitro kinase activity measurement of ATM (Ataxia telangiectasia mutation) or ATR (ATM - and RAD3- related). L - (+) - ergot has been used to: 1. As a component of the cumulus oocyte complex (COC) maturation medium, its protective effect on lipid peroxidation formation was tested; 2. As an antioxidant compound, it is used to detect type 2 diabetes patients; 3. As a positive control for soluble carrier protein 22A4 (SLC22A4) transport detection.
Chinese name
L-(+)-麦角硫因
English name
L-(+)-Ergothioneine
Chinese alias
(S)-α-羧基-N,N,N-三甲基-2-巯基-1H-咪唑-4-乙酰胆碱 内盐 | 2-巯基组氨酸三甲基甜菜碱 | 硫代组氨酸甜菜碱 | 硫因 | 硫氨酸 | 麦角硫因 | 麦角硫碱
English alias
2-mercaptohistidine trimethylbetaine | AKOS027325505 | ergothioneine (thione form) | ERGOTHIONEINE [MI] | SCHEMBL188140 | 1H-Imidazole-4-ethaniminium, alpha-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-, hydroxide, inner salt, (S)- | MFCD00167474 | (S)-3-
CAS number
497-30-3
molecular formula
C9H15N3O2S
molecular weight
229.30 g/mol
Exact mass
-
PSA
96.300 Ų
Logp
0.300
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Research chemical CAS 497-30-3 ≥95% 5g

Yuanye Research chemical CAS 497-30-3 ≥95% 5g, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S31792-5g
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