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Product introduction

SF1126是一种水溶性小分子前药，包含泛PI3K / mTOR抑制剂LY294002 / SF1101与含RGD的四肽SF1174共轭，具有潜在的抗肿瘤和抗血管生成活性。SF1126旨在在酸性pH（pH SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities. The SF1126 is designed to remain stable at acidic pH (pH

Specs ⸢ View details ⸥

Chinese name

SF1126, 丝氨酸/苏氨酸蛋白激酶 mTOR 抑制剂

English name

SF1126

Chinese alias

English alias

SF1126 | EX-A5997 | SF-1126 INNER SALT | SF 1126 | Q27276459 | SCHEMBL15668089 | 936487-67-1 | BDBM50507755 | CHEMBL2326966 | SF-1126 | (8S,14S,17S)-14-(carboxymethyl)-8-(3-guanidinopropyl)-17-(hydroxymethyl)-3,6,9,12,15-pentaoxo-1-(4-(4-oxo-8-phenyl-4H-c

CAS number

936487-67-1

molecular formula

C39H48N8O14

molecular weight

852.84 g/mol

Exact mass

≥98%

PSA

Logp

-1.5

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