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Product introduction

AG-825 是一种选择性、ATP竞争性，抑制酪氨酸磷酸化的 ErbB2 抑制剂，其 IC50 值为 0.35 μM。AG-825 具有抗癌活性。AG825 能明显加速人中性粒细胞的凋亡。AG-825 是一种潜在的克服锰诱导的神经毒性或阿尔茨海默病发展的药物。 Product description： AG-825 (Tyrphostin AG-825) is a selective and ATP-competitive ErbB2 inhibitor which suppresses tyrosine phosphorylation, with an IC50 of 0.35 μM. AG-825 displays anti-cancer activity[1][2][3]. AG825 significantly accelerates apoptosis of human neutrophils[4]. AG-825 is a potential agent for overcoming Mn-induced neurotoxicity or AD development. Application： Tyrphostin AG 825 has been used to study its effects on iodide uptake in EMT6 cells.

Specs ⸢ View details ⸥

Chinese name

AG 825,ErbB2抑制剂

English name

AG 825

Chinese alias

3-[3-[(2-苯并噻唑硫基)甲基]-4-羟基-5-甲氧基苯基]-2-氰基-2-丙烯酰胺 | 酪氨酸磷酸化抑制剂AG825

English alias

(E)-3-(3-((benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide | SR-01000597586 | HMS1362L03 | Q27145279 | 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide | AG 825 | CCG-100612 | IDI1_002186 | Tyrph

CAS number

149092-50-2

molecular formula

C19H15N3O3S2

molecular weight

397.47 g/mol

Exact mass

≥96%

PSA

163.000 Å²

Logp

3.600

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MedMol AG-825 98% 5mg

Name: MedMol AG-825 98% 5mg
Brand: MedMol
SKU: S34181-5mg

MedMol AG-825 98% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：S34181-5mg

Product model：5mg

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Lead Time：30days

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MedMol AG-825 98% 5mg

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