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Product introduction

SB 216763 SB 216763是有效，选择性和ATP竞争性的 GSK-3 抑制剂，抑制GSK-3α和GSK-3β的 IC50 为34.3 nM。 SB 216763 SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line 6 and colorectal cancer cells. 7 SB-216763 was used to inhibit GSK-3β in human brain microvascular endothelial cell line and colorectal cancer cells.

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Chinese name

SB216763,GSK3抑制剂, 糖原合酶激酶 3 alpha 抑制剂

English name

SB216763

Chinese alias

English alias

FT-0688716 | B5716 | CHEBI:91421 | GTPL8015 | Lopac-S-3442 | Q4918914 | Z2065671802 | 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione;SB-216763 | C19H12Cl2N2O2 | CCG-101287 | SDCCGSBI-0050908.P002 | NCGC00015949-01 | NCGC00025232-02 | LP009

CAS number

280744-09-4

molecular formula

C19H12N2O2Cl2

molecular weight

371.22 g/mol

Exact mass

PSA

51.100 Å²

Logp

3.9

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