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Product introduction

SB408124是一种非肽类OX1 receptor拮抗剂，作用于全细胞和膜，Ki分别为57 nM和27 nM，比作用于OX2受体选择性高50倍 SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor A selective non-peptide orexin R-1 receptor inhibitor

Specs ⸢ View details ⸥

Chinese name

SB408124, OX 1 受体拮抗剂

English name

SB408124

Chinese alias

English alias

BCP02343 | CCG-268112 | SCHEMBL1586538 | BDBM50423648 | N-(6,8-DIFLUORO-2-METHYL-4-QUINOLINYL)-N'-[4-(DIMETHYLAMINO)PHENYL]UREA | NCGC00025330-02 | Q7388912 | C19H18F2N4O | HMS3884O19 | SB408124 | SB-408124 | 1-[6,8-bis(fluoranyl)-2-methyl-quinolin-4-yl]-

CAS number

288150-92-5

molecular formula

C19H18F2N4O

molecular weight

356.37 g/mol

Exact mass

PSA

57.300 Å²

Logp

3.500

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