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Product introduction
血根碱是一种苯并菲啶生物碱、生物碱抗生素和植物抗真菌剂。
Chinese name
血根碱, G 蛋白信号调节抑制剂 17
English name
24-methyl-5,7,18,20-tetraoxa-24-azoniahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene
Chinese alias
血根碱 | 假白屈菜季铵碱
English alias
CHEBI:17183 | sangvinarin | AB00053789_04 | compound 1 [PMID: 28621943] | BDBM25525 | NCGC00015959-04 | 13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium nitrate | NCGC00015959-03 | UI5 | Benzophenanthridine alkaloid | Q-100313 | SCHEMB
CAS number
2447-54-3
molecular formula
C20H14NO4+
molecular weight
332.3
Exact mass
-
PSA
40.8
Logp
4.4
Safety
  • Toxicity summary: 血根碱在微摩尔浓度下,通过诱导凋亡,对人鳞状癌细胞(A431)产生细胞生长抑制反应。与此同时,在相似剂量下,血根碱处理不会导致正常人表皮角质形成细胞的凋亡。研究发现,血根碱[0.1 (M-2 (M)]处理以剂量依赖性方式抑制HaCaT细胞增殖,并通过3-(4,5二甲基噻唑-2-基)-2,5-二苯基四唑溴化物测定和ELISA分别诱导凋亡。血根碱处理还导致HaCaT细胞中多聚(ADP-核糖)聚合酶显著裂解。血根碱处理HaCaT细胞导致剂量依赖性(a) Bax水平增加同时Bcl-2水平降低和(b)...
  • Primary Hazards: 未分类
  • Hazard categories and classifications: 未分类
  • Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
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Research chemical 1ml

Research chemical 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.

item number:S422828-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 641 Items
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1ml

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