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Product introduction
Selumetinib (AZD6244)是一种有效,高选择性的MEK1抑制剂,IC50为14 nM,也抑制ERK1/2磷酸化,IC50为10 nM,对p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf等没有抑制作用。Phase 3。A MEK-1 non-ATP competitive inhibitor. Selumetinib (AZD6244) is a potent, highly selective MEK1 inhibitor with IC50 of 14 nM, also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Phase 3. A MEK-1 non-ATP competitive inhibitor.
Chinese name
司美替尼 (AZD6244), 双特异性丝裂原活化蛋白激酶激酶 2 抑制剂
English name
Selumetinib (AZD6244)
Chinese alias
-
English alias
6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy -ethoxy)-amide | AZD6244 (Selumetinib) | BCPP000367 | EX-A020 | HMS3244G03 | 5-[(4-BROMO-2-CHLOROPHENYL)AMINO]-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-1H-BENZI
CAS number
606143-52-6
molecular formula
C17H15BrClFN4O3
molecular weight
457.69 g/mol
Exact mass
-
PSA
88.400 Ų
Logp
3.6
Technical Documents
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Selumetinib (AZD6244) ≥99% 100mg

Yuanye Selumetinib (AZD6244) ≥99% 100mg, CAS 606143-52-6, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S48914-100mg
Product model:100mg
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Lead Time:30days
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