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Product introduction
AZD8931 (Sapitinib)是一种可逆的,ATP竞争性EGFR, ErbB2和ErbB3抑制剂,IC50分别为4 nM, 3 nM和4 nM,作用于NSCLC细胞比Gefitinib或Lapatinib更有效,作用于ErbB家族比作用于MNK1和Flt选择性强100倍。A potent inhibitor of EGFR phosphorylation. AZD8931 is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM, more potent than Gefitinib or Lapatinib against NSCLC cell, 100-fold more selective for the ErbB family than MNK1 and Flt. A potent inhibitor of EGFR phosphorylation.
Chinese name
沙匹替尼, 表皮生长因子受体 erbB1 抑制剂
English name
AZD8931 (Sapitinib)
Chinese alias
-
English alias
4-AMINOmethylbenZAMIDINE dihydrochloride | BCP9000357 | GTPL7717 | AS-17066 | BCPP000365 | Sapitinib [INN] | s2192 | AZD 8931 | BDBM50437353 | DB12183 | NCGC00346573-05 | NSC758005 | NSC-758005 | 1-boc-2-(aminomethyl)-pyrrolidine | AZD-8931(Sapitinib) | D
CAS number
848942-61-0
molecular formula
C23H25ClFN5O3
molecular weight
473.93 g/mol
Exact mass
-
PSA
88.600 Ų
Logp
4
Technical Documents
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AZD8931 (Sapitinib) ≥98% 1mg

Yuanye AZD8931 (Sapitinib) ≥98% 1mg, CAS 848942-61-0, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S51159-1mg
Product model:1mg
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Lead Time:30days
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