Reagent used for; 1.Sequential Suzuki cross-coupling reactions. 2.Copper-catalyzed oxidative trifluoromethylthiolation of aryl boronic acids. 3.Directed metalation and regioselective functionalization of 3-bromofuran and related heterocycles. 4.Barton-Zard pyrrole cyclocondensations and Baeyer-Villiger oxidations. 5.Diplar cycloaddition and palladium-catalyzed cross-coupling processes. Reagent used in Preparation of; 1.Diarylaminopyridines as potential anti-malarial agents. 2.Hydropyranopyrazine via chloropyrazinecarboxaldehyde and olefination. 3.Biaryl sulfone derivatives as antagonists of the histamine H3 receptor. 4.Novel kinase inhibitor scaffolds with potential antitumor effects. 5.Hepatitis C virus inhibition activity of N-hydroxyisoquinoline diones.