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名称

SARS-CoV-2-IN-13

分子类型

未知

英文名称

SARS-CoV-2-IN-13

货号

S647437-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

SARS-CoV-2-IN-13 (compound 5) is a potent inhibitor of SARS-CoV-2 with an IC 50 of 0.057 μM. SARS-CoV-2-IN-13 is a niclosamide analogue. SARS-CoV-2-IN-13 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally. Form:Solid

生化机理

SARS-CoV-2-IN-13 （化合物 5）是一种强效的 SARS-CoV-2 抑制剂，其 IC 50 为 0.057 μM。SARS-CoV-2-IN-13 是一种烟酰胺类似物。与尼可刹米相比，SARS-CoV-2-IN-13 在人体血浆和肝脏 S9 酶测定中具有更高的稳定性，能对 SARS-CoV-2 产生更强的抑制作用。

CAS号

56961-10-5

分子式

C13H8Cl2N2O4

分子量

327.12 g/mol

Smiles

O=C(C1=C(C=CC(Cl)=C1)O)NC2=CC(Cl)=C(C=C2)[N+]([O-])=O

溶解性

DMSO : ≥ 125 mg/mL (382.12 mM)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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