Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

Sirt2-IN-1

分子类型

小分子

英文名称

Sirt2-IN-1

货号

S648160-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

Sirt2-IN-1 (Compound 9) is a sirtuin 2 ( Sirt2 ) inhibitor with an IC 50 of 163 nM Form:Solid IC50& Target:SIRT2 163 nM (IC 50 )

生化机理

Sirt2-IN-1 （化合物 9）是一种 sirtuin 2 （Sirt2）抑制剂，其 IC 50 为 163 nM。

CAS号

1862238-00-3

分子式

C28H27N7O2S2

分子量

557.69 g/mol

PubChem编号

112499922

Isomeric SMILES

CC1=CC(=NC(=N1)SCC(=O)NC2=NC=C(S2)CC3=CC(=CC=C3)OCC4=CN(N=N4)CC5=CC=CC=C5)C

IIUPAC Name

N-[5-[[3-[(1-benzyltriazol-4-yl)methoxy]phenyl]methyl]-1,3-thiazol-2-yl]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamide

INCHI

1S/C28H27N7O2S2/c1-19-11-20(2)31-28(30-19)38-18-26(36)32-27-29-14-25(39-27)13-22-9-6-10-24(12-22)37-17-23-16-35(34-33-23)15-21-7-4-3-5-8-21/h3-12,14,16H,13,15,17-18H2,1-2H3,(H,29,32,36)

InChi Key

YWLNYZXFIAFWSF-UHFFFAOYSA-N

Smiles

CC1=CC(=NC(=N1)SCC(=O)NC2=NC=C(S2)CC3=CC(=CC=C3)OCC4=CN(N=N4)CC5=CC=CC=C5)C

PubChem CID

112499922

溶解性

DMSO : 150 mg/mL (268.97 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

557.167 Da

单同位素质量Monoisotopic Mass

557.167 Da

拓扑极表面积Topological Polar Surface Area

161.000 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

751

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

4.9

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！