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Product introduction

SNIPER(BRD)-1, consists of an IAP antagonist LCL-161 derivative and a BET inhibitor, (+)-JQ-1, connected by a linker. SNIPER(BRD)-1 induces the degradation of BRD4 via the ubiquitin-proteasome pathway. SNIPER(BRD)-1 also degrades cIAP1 , cIAP2 and XIAP with IC 50 s of 6.8 nM, 17 nM, and 49nM, respectively Form:Solid IC50& Target:BRD4 cIAP1 6.8 nM (IC 50 ) cIAP2 17 nM (IC 50 ) XIAP 49 nM (Ki) SNIPER

Specs ⸢ View details ⸥

Chinese name

SNIPER(BRD)-1

English name

SNIPER(BRD)-1

Chinese alias

狙击手(BRD)-1

English alias

CAS number

2095244-54-3

molecular formula

C53H66ClN9O8S2

molecular weight

1056.73 g/mol

Exact mass

≥99%

PSA

Logp

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