Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

Sisunatovir hydrochloride

分子类型

小分子

别名

盐酸西舒那韦

英文别名

1'-((5-(Aminomethyl)-1-(4,4,4-trifluorobutyl)-1H-benzimidazol-2-yl)methyl)-6'-fluoro-spiro(cyclopropane-1,3'-(3H)indol)-2'(1'H)-one monohydrochloride | AKOS040759721 | Sisunatovir HCl | Sisunatovir hydrochloride [USAN] | 1'-[[5-(aminomethyl)-1-(4,4,4-trif

英文名称

Sisunatovir hydrochloride

货号

S650948-5mg

包装规格

5mg

浓度

≥98%

储存温度

2-8°C储存,干燥

运输条件

冰袋运输

产品介绍

Sisunatovir (RV521) hydrochloride, an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC 50 s of 1.4 nM and 1.0 nM, respectively. Form:Solid

生化机理

盐酸西舒那托韦（RV521）是一种可口服的 RSV 融合（RSV-F）蛋白抑制剂，对 RSV-A 和 RSV-B 病毒的临床分离株具有很强的疗效，IC 50 s 分别为 1.4u2009nM 和 1.0u2009nM。

CAS号

1903763-83-6

分子式

C23H23ClF4N4O

分子量

482.90 g/mol

PubChem编号

153520065

Isomeric SMILES

C1CC12C3=C(C=C(C=C3)F)N(C2=O)CC4=NC5=C(N4CCCC(F)(F)F)C=CC(=C5)CN.Cl

IIUPAC Name

1'-[[5-(aminomethyl)-1-(4,4,4-trifluorobutyl)benzimidazol-2-yl]methyl]-6'-fluorospiro[cyclopropane-1,3'-indole]-2'-one;hydrochloride

INCHI

1S/C23H22F4N4O.ClH/c24-15-3-4-16-19(11-15)31(21(32)22(16)7-8-22)13-20-29-17-10-14(12-28)2-5-18(17)30(20)9-1-6-23(25,26)27;/h2-5,10-11H,1,6-9,12-13,28H2;1H

InChi Key

NYYYAFKAHRIPJW-UHFFFAOYSA-N

Smiles

C1CC12C3=C(C=C(C=C3)F)N(C2=O)CC4=NC5=C(N4CCCC(F)(F)F)C=CC(=C5)CN.Cl

PubChem CID

153520065

关联CAS

1903763-83-6

溶解性

DMSO : 100 mg/mL (207.08 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

482.15 Da

单同位素质量Monoisotopic Mass

482.15 Da

拓扑极表面积Topological Polar Surface Area

64.200 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

715.000

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！