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Product introduction

SGK1-IN-1 is a highly active and selective inhibitor of SGK-1 , with an IC 50 of 1 nM. In Vitro SGK1-IN-1 (14n) shows an acceptable SGK isoform selectivity with a good activity on hSGK2 and a moderate activity on the hSGK3, with IC 50 s of 1, 41 nM at 10 μM and 50 μM ATP concentration, respectively. SGK1-IN-1 also displays cellular activity in a SGK1-dependent phosphorylation of GSK3β assay in U2OS cells with activities of 0.69 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:SGK1

Specs ⸢ View details ⸥

Chinese name

SGK1-IN-1

English name

SGK1-IN-1

Chinese alias

English alias

CAS number

1279829-87-6

molecular formula

C17H12ClFN6O2S

molecular weight

418.83 g/mol

Exact mass

≥99%

PSA

135.000 Å²

Logp

2.400

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