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Product details

名称

SB-612111 hydrochloride

别名

SB-612111盐酸盐

英文名称

SB-612111 hydrochloride

货号

S661595-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

SB-612111 hydrochloride hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 ( K i =0.33 nM). SB-612111 hydrochloride exhibits selectivity for μ-, κ- and δ-receptors with K i values of IC50& Target:NOP Receptor/ORL1 In Vivo:SB-612111 hydrochloride (intravenous injection; 0.6-10 nmol/mouse) antagonize nociceptin-induced thermal hyperalgesia in a dose-dependent manner with an ED 50 of 0.62mg/kg. SB-612111 hydrochloride (intravenous injection; 0.1-5mg/kg) causes a signif Biological Activity:SB-612111 hydrochloride hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 ( K i =0.33 nM). SB-612111 hydrochloride exhibits selectivity for μ-,xa0κ- andxa0δ-receptors with K i value

分子式

C24H30Cl3NO

分子量

454.86 g/mol

Smiles

O[C@H]1C[C@@H](CN2CCC(C3=C(Cl)C=CC=C3Cl)CC2)CCC4=C(C)C=CC=C41.[H]Cl

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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