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名称

α-2,6-唾液酸转移酶来源于美人鱼发光杆菌

货号

S755123-1unit

包装规格

1unit

级别

重组

浓度

expressed in E. coli BL21,≥5 units/mg protein

产品介绍

α来自美人鱼发光杆菌（Photobacterium damsela）的-2,6-唾液酸转移酶已被用于HRT-18G细胞中唾液酸（SA）的再唾液酸化（resialylation）和恢复。高活性α 2-6唾液酸转移酶已用于制备高级别的的二唾液酸化片段晶体。应用：人ST6Gal-1（β半乳糖苷α-2,6-唾液酸转移酶1）是CAZy家族GT29的成员。 Human ST6Gal-I (β-galactoside α-2,6-sialyltransferase 1) is a member of the CAZy family GT29. Application: α-2,6-Sialyltransferase from Photobacterium damsela has been used in resialylation and restoration of sialic acids (SAs) in HRT-18G cells. Highly active α2-6 sialyltransferase has been used to prepare high levels of disialylated fragment crystals.

生化机理

α复杂的N-聚糖生物合成的最终步骤是由-2,6-唾液酸转移酶（ST）催化。与真核生物α（2,6）-ST相比，细菌α（2,6）-ST具有更广泛的受体底物特异性。唾液酸转移酶可将Neu5Ac从CMP-Neu5Ac转移至受体分子（包括糖蛋白、糖脂和寡糖）的半乳糖基末端。

Safety

「No Dangerous Attributes」

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