- Harmful effect： 与布美他尼最常见的不良事件包括高尿酸血症(所有袢利尿剂的特性)、低氯血症、低钾血症、氮质血症和低钠血症。其他较少见的不良反应包括高血糖、血清肌酐升高、肌无力和听力损害。罕见但重要或可能危及生命的严重不良反应包括低血压(包括体位性低血压)、脑病(在已有肝病患者中)和肾功能衰竭。所有袢利尿剂都具有强大的利尿能力，过量使用可导致显著的利尿和体液及电解质流失；使用这些药物时需要密切的医疗监督。
- Toxicity summary： 过度或过于频繁的剂量可导致急性容量和电解质耗竭，循环血容量降低，可能伴有血管血栓形成和栓塞。由于电解质耗竭，可能出现虚弱、精神错乱、食欲不振、嗜睡、呕吐和痉挛等症状。治疗方法是充分补充液体和电解质，如钾耗竭时补充钾制剂或保钾利尿剂。也可能出现无症状的高尿酸血症和可逆的血尿素氮(BUN)和肌酐轻度升高，尤其与脱水或肾功能不全患者相关。布美他尼已显示增加尿钙，导致低钙血症。同样，应定期测量低镁血症。
- Other safety information： 化学品评估：IMAP评估 - 苯甲酸，3-(氨基磺酰基)-5-(丁基氨基)-4-苯氧基-：环境I级评估
- Hazard categories and classifications： 代表物2 (25%)
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： 截至修订日期，未找到布美他尼的相关已发表信息。产后立即使用强效利尿剂、限制液体摄入和乳房压迫已被用于抑制泌乳。利尿剂对其他有效抑制泌乳措施的附加贡献尚未研究。尚无关于袢利尿剂对已建立的持续泌乳的影响的数据。
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Research chemical 99% 1g
Research chemical 99% 1g, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
