- exposure pathway： 眼部插入后全身吸收极少。当外用凝胶应用于与酒渣鼻相关的面部红斑成人患者时，血浆最大浓度(Cmax)和浓度-时间曲线下面积(AUC)分别为46 ± 62 pg/mL和417 ± 264 pg.hr/mL。这些数值在治疗第15天达到。
- Toxicity summary： 溴莫尼定是一种α肾上腺素能受体激动剂（主要是α-2型）。它在给药后两小时达到眼压降低的峰值。在动物和人体中的荧光光度研究表明，溴莫尼定具有双重作用机制，通过减少房水产生和增加葡萄膜巩膜外流。外用凝胶通过直接血管收缩减少红斑。
- Toxicity Data： LD50: 50 mg/kg (口服，小鼠) LD50: 100 mg/kg (口服，大鼠)
- Symptoms and Signs： 口服LD<sub>50</sub>在小鼠中为50 mg/kg，在大鼠中为100 mg/kg。
- Hazard categories and classifications： 急性毒性 3级 (100%)
- Carcinogen Classification： 对人类无致癌性迹象（未被IARC列出）。
- Effects During Pregnancy and Lactation： 截至修订日期，未找到相关已发表信息。
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MedMol Brimonidine Tartrate 98% 5mg
MedMol Brimonidine Tartrate 98% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
