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Product introduction
Information "Belizatinib (TSR-011) is a potent inhibitor ofALK(IC50=0.7 nM) andtropomyosin receptor kinase (TRK)(IC50 values less than 3 nM for TRK A, B, and C). " Targets TrkA ; TrkB ; TrkC ; TrkA ; TrkB 28040,; In vitro TSR-011 has high affinity for wild-type recombinant ALK kinase activity, with an IC50 value of 0.7\u2009nM and inhibits tropomyosin receptor kinase (TRK) A, B, and C (IC50 In vivo TSR-011 exerts sustained potent inhibition of ALK-dependent tumour growth in mouse models. It is well-tolerated.
Chinese name
贝扎替尼(TSR-011), ALK 受体酪氨酸激酶抑制剂
English name
Belizatinib (TSR-011)
Chinese alias
-
English alias
1357920-84-3 | AKOS037648708 | BCP29521 | Belizatinib [WHO-DD] | D80502 | EX-A1509 | SCHEMBL22567114 | SCHEMBL573248 | BDBM50396243 | BDBM513991 | s8511 | SCHEMBL19328244 | Belizatinib(TSR-011) | SCHEMBL573249 | GTPL10474 | Belizatinib (TSR011) | Belizati
CAS number
1357920-84-3
molecular formula
C33H44FN5O3
molecular weight
577.73 g/mol
Exact mass
-
PSA
99.500 Ų
Logp
4.827
Technical Documents
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Research chemical 99% 5mg

Research chemical 99% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S82979-5mg
Product model:5mg
level: 99% 5mg
Lead Time:30days
sold 541 Items
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