Val-Cit-PAB-MMAE 是抗体偶联活性分子 ADC 的一部分，由 ADC linker (peptide Val-Cit-PAB) 和强效微管蛋白抑制剂 MMAE 偶联而成。 生物活性： Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization. Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate. It contains a maleimidocaproyl (MC) spacer, a protease-sensitive Val-Cit dipeptide, a PABC linker and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells.