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Product introduction
D-64131是微管蛋白聚合抑制剂,IC50值为0.53 μM。D-64131以剂量依赖的方式抑制牛脑微管蛋白的聚合以及[3H]秋水仙碱与生物素化的αβ微管蛋白的结合。使用D-64131处理后,许多癌细胞的微管结构异常,例如破碎的有丝分裂纺锤体以及多个纺锤极。D-64131处理的许多细胞中出现核起泡和异常核结构,这是凋亡细胞的典型特征。在人无色素恶性黑色素瘤MEXF989异种移植的裸鼠体内,D-64131显示出良好的耐受性和较高的活性。D-64131显著抑制治疗期间的肿瘤生长。
Chinese name
D-64131,微管蛋白聚合抑制剂
English name
D-64131
Chinese alias
(5-甲氧基-1H-吲哚-2-基)苯基甲酮
English alias
CHEBI:92475 | FT-0700358 | (5-Methoxy-1H-indol-2-yl)-phenyl-methanone | ZCA58878 | (5-Methoxy-1H-indol-2-yl)(phenyl)methanone | SR-01000597597-1 | DTXSID30397970 | ICMIJSRDISNKOC-UHFFFAOYSA-N | Tocris-1643 | HMS3676P03 | EC-000.2395 | SCHEMBL5828518 | 5-m
CAS number
74588-78-6
molecular formula
C16H13NO2
molecular weight
251.28 g/mol
Exact mass
≥97%
PSA
42.100 Ų
Logp
3.700
Technical Documents
「No technical documents」
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Research chemical CAS 74588-78-6 97% 5mg

Yuanye Research chemical CAS 74588-78-6 97% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S86392-5mg
Product model:5mg
level: 97% 5mg
Lead Time:30days
sold 111 Items
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