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Product introduction
6-羟基多巴胺盐酸盐(6-OHDA)是一种神经毒素,通常用于诱导帕金森症′(PD)。6-OHDA可导致黑质致密部的多巴胺能神经元死亡,从而渐进式模仿PD。6-OHDA是高度可氧化的,其不能穿过血脑屏障。6-OHDA可通过产生活性氧物质,引发细胞应激和细胞死亡而发挥细胞毒性。在很多 体外 模型中,如原代神经元培养、人神经母细胞瘤细胞系、以及大鼠肾上腺嗜铬细胞瘤细胞系PC12,6-OHDA会导致许多神经元细胞的死亡。 应用 6-羟基多巴胺盐酸盐已被用于: 在大鼠中诱发帕金森症′(PD) 分析6-OHDA对PC12细胞的细胞毒性 诱导来自蓝斑中的去甲肾上腺素能(NA)神经元缺失 6-Hydroxydopamine hydrochloride is a selective catecholaminergic neurotoxin. 6-Hydroxydopamine hydrochloride depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons. Causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats, producing an animal model of Parkinson's disease. A selective catecholaminergic neurotoxin.
Chinese name
6-羟基多巴胺盐酸盐
English name
6-HydroxyDopamineHydrochloride
Chinese alias
2,4,5-三羟基苯乙胺盐酸盐 | 2,5-二羟基酪胺 盐酸盐 | 2-(2,4,5-三羟基苯基)乙胺 盐酸盐
English alias
Oxidopamine (hydrochloride) | 2,4,5-Trihydroxyphenethylamine hydrochloride | Oxidopamine hydrochloride | 6-OHDA
CAS number
28094-15-7
molecular formula
(HO)3C6H2CH2CH2NH2 · HCl
molecular weight
205.64 g/mol
Exact mass
-
PSA
86.700 Ų
Logp
-
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MedMol 6-Hydroxydopamine Hydrochloride 98% 50mg

MedMol 6-Hydroxydopamine Hydrochloride 98% 50mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S88807-50mg
Product model:50mg
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Lead Time:30days
sold 645 Items
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