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Product introduction
PF-3644022 是一种有效的,选择性的,口服活性的,具有 ATP 竞争性的 MAPKAPK2 (MK2) 抑制剂,IC50 为 5.2 nM,Ki 为 3 nM。PF-3644022 还抑制 MK3 和 p38 调节/激活激酶 (PRAK),IC50 分别为 53 nM 和 5.0 nM。PF-3644022 有效抑制 TNFα 的产生并具有抗炎作用。
Chinese name
PF 3644022,MK2抑制剂, MAPK 活化蛋白激酶 2 抑制剂
English name
PF 3644022
Chinese alias
-
English alias
(10R)-9,10,11,12-Tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one | PF-3644022 | (R)-10-methyl-3-(6-methylpyridin-3-yl)-11,12-dihydro-10H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-ol
CAS number
1276121-88-0
molecular formula
C21H18N4OS
molecular weight
374.46 g/mol
Exact mass
-
PSA
95.200 Ų
Logp
4.000
Technical Documents
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MedMol PF-3644022 98% 100mg

MedMol PF-3644022 98% 100mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S89175-100mg
Product model:100mg
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Lead Time:30days
sold 402 Items
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