NSC 694621 is a potent PCAF inhibitor, with an IC 50 of 5.71 µM ( PCAF/H3 1-21 ). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells In Vitro NSC 694621 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: SK-N-SH, HCT116 cells Concentration: 25 µM Incubation Time: 72 h Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI 50 of 19.2 µM and growth inhibition of 29%, respectively. Form:Solid IC50& Target:IC50: 5.71 µM (PCAF/H3 1-21 )