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Product introduction

SC144 hydrochloride 是首创的口服活性 gp130 (IL6-beta) 抑制剂。SC144 hydrochloride 结合 gp130，诱导 gp130 磷酸化(S782) 和去糖基化，消除 Stat3 磷酸化和核易位，进一步抑制下游靶基因的表达。SC144 hydrochloride 对 gp130 配体触发的信号转导有明显的抑制作用。SC144 hydrochloride 诱导人卵巢癌细胞凋亡。 Application： SC144 hydrochloride has been used: as a glycoprotein 130 (gp130) inhibitor to evaluate the effect of bazedoxifene on interleukin (IL-6) mediated cell viability in pancreatic cancer cells as a gp130 inhibitor to study its effects on signal transducer and activator of transcription 3 (STAT3) activation in mesenchymal precursor cells (KMM) cells as an interleukin 6 signal transducer (IL-6ST) inhibitor in media to test its ability to block serum-induced migration/invasion

Specs ⸢ View details ⸥

Chinese name

SC 144 盐酸盐

English name

SC 144 hydrochloride

Chinese alias

2-(7-氟吡咯并[1,2-a]喹喔啉-4-基)2-吡嗪羧酸酰肼盐酸盐

English alias

CAS number

917497-70-2

molecular formula

C16H11FN6O•HCl

molecular weight

358.76 g/mol

Exact mass

≥98%(HPLC)

PSA

84.200 Å²

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SC144 Hydrochloride 98% 5mg

Name: SC144 Hydrochloride 98% 5mg
Brand: 麦克林
SKU: S911615-5mg

SC144 Hydrochloride 98% 5mg CAS 917497-70-2, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：S911615-5mg

Product model：5mg

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Lead Time：30days

sold 422 Items

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SC144 Hydrochloride 98% 5mg

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