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Product introduction
脂蛋白A4 (LXA4) 是一种内源性脂氧合酶衍生的类二十烷酸调节剂,具有强大的抗炎和促消炎双重特性。Lipoxin A4 抑制与 ERK1/2 和 NF-kB 通路相关的人表皮角质形成细胞 (NHEK) 的增殖以及炎性细胞因子/趋化因子(如IL-6,IL-8等)的产生。Lipoxin A4 抑制血清淀粉样蛋白 A (SAA) 介导的 IL-8 释放,IC50 值为 25.74 nM。 Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM.
Chinese name
脂氧素 A4, FPR2/ALX 激动剂
English name
Lipoxin A4
Chinese alias
-
English alias
(7E,9E,11Z,13E)-(5S,6R,15S)-5,6,15-Trihydroxyicosa-7,9,11,13-tetraenoate | GTPL1034 | 7,9,11,13-Eicosatetraenoic acid, 5,6,15-trihydroxy-, (5S,6R,7E,9E,11Z,13E,15S)- | F7C6J3D79J | NCGC00161280-03 | (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-trihydroxyeicosa-7,9,11
CAS number
89663-86-5
molecular formula
C20H32O5
molecular weight
352.47 g/mol
Exact mass
-
PSA
98.000 Ų
Logp
3.100
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5S, 6R-LipoxinA4 ≥95%, 100µg/mL in ethanol 25μg

5S, 6R-LipoxinA4 ≥95%, 100µg/mL in ethanol 25μg CAS 89663-86-5, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S912990-25μg
Product model:25μg
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Lead Time:30days
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