（2'S）-尼古丁1氧化物是在烟草，烟叶和樟子松的叶，茎和根中发现的尼古丁衍生物。还已经确定它是动物和人体内尼古丁的代谢产物。 (2'S)-Nicotine 1-Oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. It has also been identified as metabolites of nicotine in animals and in human. application： Nicotine-1’-N-oxide is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.