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Product introduction

SBI-477 是一种 insulin signaling 的抑制剂，可使转录因子 MondoA 失活，从而导致胰岛素途径抑制剂 thioredoxin-interacting protein (TXNIP) 和 arrestin domain-containing 4 (ARRDC4) 的表达降低。SBI-477 抑制人骨骼肌细胞中 triacylglyceride (TAG) 的合成并增强基础葡萄糖的摄取。靶点 MondoA ; TXNIP ; ARRDC4 ; TAG Information SBI-477 SBI-477 is an insulin signaling inhibitor that deactivates the transcription factor MondoA , leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4) . SBI-477 inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes. Targets MondoA ; TXNIP ; ARRDC4 ; TAG

Specs ⸢ View details ⸥

Chinese name

SBI-477

English name

SBI-477

Chinese alias

English alias

3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide

CAS number

781628-99-7

molecular formula

C24H25N3O6S

molecular weight

483.54 g/mol

Exact mass

≥98%

PSA

127.000 Å²

Logp

2.900

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SBI-477 98% 5mg

Name: SBI-477 98% 5mg
Brand: 麦克林
SKU: S999592-5mg

SBI-477 98% 5mg Macklin 781628-99-7, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number：S999592-5mg

Product model：5mg

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Lead Time：30days

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SBI-477 98% 5mg

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