2,5-Thiophenedicarboxaldehyde can be prepared from 2,5-bis(chloromethyl)thiophene by the application of Krohnke′s method.2,5-Thiophenedicarboxaldehyde may be employed in the following studies: · Asymmetric synthesis of bis-homoallylic alcohols. · Synthesis of new symmetrical arylene bisimide derivatives. · As dialdehyde monomer in the synthesis of silicon-containing poly(p-phenylenevinylene)-related copolymers having uniform p-conjμgated segment regulated by organosilicon units. · Synthesis of 2,5-bis[2-(5-N-isopropylamidino)benzimidazoyl]thiophene hydrochloride. 2,5-Thiophenedicarboxaldehyde can be prepared from 2,5-bis(chloromethyl)thiophene by the application of Krohnke′s method. 2,5-Thiophenedicarboxaldehyde may be employed in the following studies: · Asymmetric synthesis of bis-homoallylic alcohols. · Synthesis of new symmetrical arylene bisimide derivatives. · As dialdehyde monomer in the synthesis of silicon-containing poly(p-phenylenevinylene)-related copolymers having uniform p-conjugated segment regulated by organosilicon units. · Synthesis of 2,5-bis[2-(5-N-isopropylamidino)benzimidazoyl]thiophene hydrochloride.