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Product introduction
氢氟噻嗪是一种苯并噻二嗪,由3,4-二氢-HH-1,2,4-苯并噻二嗪双环系统构成,硫被双氧合化,在6位和7位分别带有三氟甲基和氨基磺酰基团。一种利尿剂,具有与氢氯噻嗪相似的作用和用途。它具有利尿剂和抗高血压药的作用。它是一种噻嗪和苯并噻二嗪。
Chinese name
氢氟噻嗪
English name
1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
Chinese alias
-
English alias
3,4-Dihydro-6-trifluoromethyl-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide; 3,4-Dihydro-6-trifluoromethyl-2H-1,2,4-benzothiazide-7-sulfonamide1,1-dioxide; 3,4-Dihydro-6-trifluoromethyl-7-sulfamoylbenzo-1,2,4-thiadiazine1,1-dioxide; 3,4-Dihydro-7-sul
CAS number
135-09-1
molecular formula
C8H8F3N3O4S2
molecular weight
331.3
Exact mass
-
PSA
135
Logp
0.4
Safety
  • Storage conditions: 市售氢氟噻嗪片应储存在室温下(约25°C)...
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • Regulatory information: 新西兰EPA化学品状态清单: 2H-1,2,4-苯并噻二嗪-7-磺酰胺, 3,4-二氢-6-(三氟甲基)-, 1,1-二氧化物: 没有单独批准但可在适当的团体标准下使用
  • Human toxicity extract: 可能抑制泌乳,但与母乳喂养兼容/SRP:/。/噻嗪类利尿剂,来自表格/
  • Other safety information: 化学评估: IMAP评估 - 2H-1,2,4-苯并噻二嗪-7-磺酰胺, 3,4-二氢-6-(三氟甲基)-, 1,1-二氧化物: 环境I级评估
  • Hazard categories and classifications: 呼吸致敏物 1 (97.6%)
  • Antidote and first aid: 噻嗪类利尿剂过量应立即进行胃排空,然后进行支持性对症治疗,并监测血清电解质浓度和肾功能。/噻嗪类利尿剂/
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2016.02.015
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到关于氢氟噻嗪的相关已发表信息。噻嗪类和噻嗪样利尿剂、限制液体摄入和乳房束缚已被用于抑制产后泌乳。利尿剂对这些有效抑制泌乳措施的附加作用尚未研究。尚无关于利尿剂对已建立的持续泌乳的影响的数据。
Related
upstream information
Manufacturing method:
间-氨基三氟甲苯(CID:7375); 氯磺酸(CID:24638); 氨(CID:222); 甲醛(CID:712)
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Research chemical CAS 135-09-1 98%; 100mg

Research chemical CAS 135-09-1 98%; 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 98%; 100mg.

item number:T14863-100mg
Product model:100mg
level: 98%; 100mg
Lead Time:30days
sold 296 Items
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