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Product introduction
Niraparib (MK4827)是一种口服有效的选择性PARP-1和PARP-2抑制剂,可在有BRCA和PTEN功能缺陷的临床肿瘤模型中引起合成致死性。Niraparib 可形成PARP–DNA复合物并导致DNA损伤、凋亡和细胞死亡。 MK-4827(Niraparib) Hcl is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
Chinese name
盐酸尼拉帕利
English name
Niraparib hydrochloride
Chinese alias
尼拉帕利盐酸盐 | 尼拉帕尼盐酸盐 | 苯甲酸尼拉帕利
English alias
EX-A1407 | AC-35440 | (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrochloride | MK-4827 (HCl) | MK 4827 | MK 4827 hydrochloride | DTXSID60146130 | MFCD20502397 | 2-(4-((3S)-Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrochloride |
CAS number
1038915-64-8
molecular formula
C19H20N4O.HCl
molecular weight
356.85 g/mol
Exact mass
≥98%
PSA
72.900 Ų
Logp
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Research chemical CAS 1038915-64-8 ≥98% 10mg

Yuanye Research chemical CAS 1038915-64-8 ≥98% 10mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T24202-10mg
Product model:10mg
level: ≥98% 10mg
Lead Time:30days
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