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Product introduction

NVP-2 是一种有效且具有选择性的 ATP 竞争性细胞周期蛋白依赖性激酶 9 (CDK9) 探针，可抑制 CDK9/CycT 活性，IC50 值为 0.514 nM。NVP-2 对 CDK1/CycB，CDK2/CycA 和 CDK16/CycY 激酶具有抑制作用，其 IC50 值分别为 0.584 µM，0.706 µM 和 0.605 µM。NVP-2诱导细胞凋亡 (Apoptosis)。 Product description： NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 µM, 0.706 µM, and 0.605 µM, respectively. NVP-2 induces cell Apoptosis.

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Chinese name

NVP 2, 细胞周期蛋白依赖性激酶 9 抑制剂

English name

NVP 2

Chinese alias

4-[[[[5'-Chloro-2']-[[反式-4-[[((1R)-2-甲氧基-1-甲基乙基]氨基]环己基]氨基] [2,4'-联吡啶] -6-基]氨基]甲基]四氢-2H-吡喃-4-腈

English alias

CAS number

1263373-43-8

molecular formula

C27H37ClN6O2

molecular weight

513.07 g/mol

Exact mass

PSA

104.000 Å²

Logp

4.300

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Research chemical CAS 1263373-43-8 ≥97% HPLC 5mg

Name: Research chemical CAS 1263373-43-8 ≥97% HPLC 5mg
Brand: 源叶
SKU: T24216-5mg

Yuanye Research chemical CAS 1263373-43-8 ≥97% HPLC 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T24216-5mg

Product model：5mg

level： ≥97% HPLC 5mg

Lead Time：30days

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Research chemical CAS 1263373-43-8 ≥97% HPLC 5mg

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