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Product introduction

Lck Inhibitor 是一种有效的口服活性淋巴细胞特异性激酶 (Lck) 抑制剂，对 Lck，Lyn，Src 和 Syk 激酶的 IC50 分别为 7、2.1、4.2 和 200 nM。与 MAPK，CDK 和 RSK 家族代表相比，Lck Inhibitor 对 Lck 的选择性高出 1000 倍以上。Lck Inhibitor 抑制 T 细胞增殖和关节炎模型。 Product description Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC50s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis.

Specs ⸢ View details ⸥

Chinese name

TC-S 7003,Lck抑制剂

English name

TC-S 7003

Chinese alias

6-(2,6-二甲基苯基)-2-[[4-(4-甲基-1-嘧啶基[5',4'：5,6]嘧啶基[1,2-a]苯并咪唑-5(6H)-一 | 6-(2,6-二甲基苯基)-2-[[4-(4-甲基-1-哌嗪基)苯基]氨基]-嘧啶并[5',4':5,6]嘧啶并[1,2-A]苯并咪唑-5(6H)-酮

English alias

6-(2,6-Dimethylphenyl)-2-[[4-(4-methyl-1-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one

CAS number

847950-09-8

molecular formula

C31H30N8O

molecular weight

530.62 g/mol

Exact mass

≥98%(HPLC)

PSA

82.400 Å²

Logp

5.200

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TC-S 7003, Lckinhibitor 100mg

Name: TC-S 7003, Lckinhibitor 100mg
Brand: 阿拉丁
SKU: T287339-100mg

TC-S 7003, Lckinhibitor 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100mg; ≥98%; HPLC.

item number：T287339-100mg

Product model：100mg

level： 100mg; ≥98%; HPLC

Lead Time：30days

sold 325 Items

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Specifications：

100mg

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TC-S 7003, Lckinhibitor 100mg

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